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Retatrutide and tirzepatide had superior efficacy in improving diabetic kidney disease, blood sugar control, and body weight management

Strong effects of GLP-1GIPLani were also observed in the skeletal muscle, with a distinct expression profile and 1,715 DEGs, particularly corresponding to enhanced oxidative phosphorylation, indicating a shift towards enhanced substrate utilization and fatty acid metabolism (Extended Data Fig

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Do not take with a high-fat meal, as this significantly increases drug absorption and raises the risk of seizure

After you reach your goal weight, youll move into the maintenance phase with continual virtual visits with your care team to help you sustain your weight loss