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244,245 DJ-1 also binds to the DNA-binding domain of p53, diminishing the DNA-binding affinity of p53 and inhibiting the expression of p53 target genes in a manner that relies on the oxidation of cysteine 106

To elucidate the potential impact of TTR amyloidosisassociated oxidative stress on GSH homeostasis, we quantified plasma PGA levels in three well-defined cohorts aged 55 years and older: asymptomatic carriers of the TTR-V30M mutation, symptomatic carriers with confirmed TTR amyloidosis (TTR-V30M patients), and healthy controls with the wild-type TTR genotype

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The MRTF-A/miR-155/SOX1 pathway mediates gastric cancer migration and invasion

It is a component of two essential cofactors used by numerous cellular enzymes, including methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in folate and homocysteine metabolism

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