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1 Introduction Coronary heart disease (CHD) represents a significant threat to global health, characterized by complex and multifactorial pathogenesis ( The pathophysiological significance of ferroptosis in cardiovascular disease stems from its multifaceted involvement in abnormal iron metabolism, lipid peroxidation, and ROS accumulationprocesses fundamental to the development of coronary artery disease (CAD)

Funding Acquisition, R.S

doi: 10.1093/stmcls/sxad074 40 WangYWangLMaSChengLYuG

The 33.5% improvement rate with associated 1.9% mortality is noteworthy, particularly given that these patients had higher baseline disease severity (median MELD-3 18.7) compared to those who worsened (median MELD-3 16.4)

This ongoing inflammation and mycotoxin exposure contribute to the development and persistence of chronic symptoms

32 ChiangH.OhnoN.HsiehY