nordisk semaglutide Novo Nordisk's Ozempic® pill, the only FDA-approved oral peptide GLP-1 medication for adults with type 2 diabetes, soon to be available in the US Novo Nordisk's semaglutide shows promise

GLP-1 medications in particular are sensitive to disruption

May 13, 2025

however, new technologies like chemical modifications (e.g., cyclic peptides), nanoparticles, and specific absorption enhancers (like SNAC in Ozempic's oral version, Rybelsus) are making oral delivery possible for certain therapeutic peptides, like semaglutide (Wegovy/Ozempic), transforming them from injections to convenient tablets, though many supplements lack strong evidence

GLP-1 is a naturally occurring hormone released in response to eating

A nested case-control study using the UK Clinical Practice Research Datalink (N=2,754 breast cancer cases in women taking spironolactone) found no statistically significant association between spironolactone use and breast cancer incidence (adjusted odds ratio 1.04 to 95% CI 0.91 to 1.18) [18]

Atkinson, PhD