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It has been approved by the Medicines and Healthcare products Regulatory Agency (MHRA) for both weight management and as a treatment for type 2 diabetes

Tirzepatide is sold as Zepbound for chronic weight management and as Mounjaro for type 2 diabetes, working as a dual GLP-1/GIP receptor agonist that targets both the GLP-1 and GIP receptors instead of GLP-1 alone, which enhances fat metabolism and insulin sensitivity beyond a single-receptor peptide

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GLP-1 also helps slow down digestion

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In terms of patient characteristics, the reduction in prostate cancer risk with GLP-1RAs is more significant in older male patients, and the expression of endogenous GLP-1 receptors has been linked to cancer risk