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Anti-inflammatory therapy ameliorates leukocyte adhesion and microvascular flow abnormalities in transgenic sickle mice

612 Aged animals are more responsive to NAD + replenishment by NMN treatment than the young one due to the age-related decline in NAD + availability

Importantly, these body weight changes were not attributable to differences in food intake across the groups, as all treatments showed similar food consumption patterns in both lean and obese mice