Cells treated with test compounds were washed with PBS and incubated with 10 M 2,7-dichlorofluorescein diacetate (DCFH-DA) at 37 C for 30 min, followed by washing with PBS, digestion with trypsin, and collection
Peptides are short chains of amino acids that act as signaling molecules in the body, directing cells and tissues to perform specific functions
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Another important outcomes of the study by Gleave and colleagues, showed that men treated with dutasteride (doses 0.5 mg daily or higher) for 4 months prior to radical prostatectomy had significantly lower intraprostatic DHT concentrations, but had higher testosterone concentrations than in untreated prostatectomies [40]