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We fused a signal peptide (SP) and a furin-cleavable sequence (FCS) to the upstream region of the Exe4 gene to enable Exe4 secretion from the edited liver

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Ozempic is administered via subcutaneous injection once a week using prefilled pen

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In order to investigate cell autonomous effects of G49 in WAT lipolysis, we isolated white adipocytes and, as shown in Fig

In the male reproductive system, pathological ROS has been associated with impaired spermatogenesis, hormone dysregulation, compromised sperm motility and morphology, and increased sperm DNA damage in both animal models and humans, including those undergoing assisted conception 51,52,53