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In the STEP trials, nausea was most common in the first 20 weeks of treatment and declined significantly after that

A vitamin B12 deficiency is seen in those who have pernicious anemia

It works by balancing key minerals like calcium, potassium and sodium, keeping blood vessels relaxed[1]

Instruct patients to discontinue RYBELSUS or OZEMPIC tablets promptly and contact their physician if pancreatitis is suspected [see Warnings and Precautions (5.2)]

Severe gastrointestinal adverse effects (persistent vomiting or diarrhoea) can lead to dehydration and, in susceptible individuals, acute kidney injury

Beta-blockers, RAAS blockers, MRAs, and diuretics each target different aspects of the disease