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Clinical trial results Sarcoidosis-associated small fiber neuropathy: In a blinded, placebo-controlled trial, 28 days of daily subcutaneous ARA-290 administration in patients with documented small nerve fiber loss produced significant improvements

O (Outcome): Primary outcome: changes in serum Vitamin B12 levels, clinical improvement of Vitamin B12 deficiency symptoms

An overview of the key features of the studies that have been included in the evaluation

Emideltide became the single instance where the committees negative outcome aligned with the staff recommendation

Some individuals with deficiency or absorption issues may need more frequent injections to maintain adequate levels of Vitamin B12 in their bodies

While B12 can be obtained through diet, some individuals may have difficulty absorbing it properly, leading to a deficiency