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Research shows this dual incretin action can significantly reduce appetite, enhance satiety, and lower caloric intake, making retatrutide a strong focus in weight-management and obesity research

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If your cycle becomes irregular, if cramps worsen, or if you experience any unexpected symptoms such as spotting, prolonged bleeding, or missed periods, its important to seek professional advice

Side effects are mostly GI symptoms, and these are much less problematic at lower doses with slow titration

Change in ONSD at M3 and M6 was not associated with the treatment group, but with ONSD at baseline (M3: \(\beta\)= 0.69, 95% CI 0.99, 0.39

However, they are still oral medications subject to the effects of delayed gastric emptying