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The interest in splitting doses usually stems from two primary challenges: managing intense side effects shortly after an injection or dealing with the return of appetite near the end of the week

These medications have been popularized and are being used in individuals who do not meet medical criteria for obesity for casual weight loss

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The combination of three-receptor GI effects with alcohol represents a higher nausea and dehydration risk than dual agonist therapy alone

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doi: 10.3389/fcell.2022.821014 39 KapoorMMartel-PelletierJLajeunesseDPelletierJPFahmiH