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Free carnitine, total carnitine, and total acylcarnitine profile Despite daily thyroid hormone replacement therapy, the congenital hypothyroid patients had been suffering from persistent fatigue

I think the reason we are seeing these increased reports of side effects (150 cases of self harm or suicidal ideation in the EU, which is a small number) is simply because more people are taking them and because people are mistaking the secondary effects of weight loss with the side effects of the drug

A meta-analysis of Phase 3 trials reported HR increases in the range of 14 beats per minute (bpm) for exenatide twice daily (BID), exenatide long-acting release (LAR), and liraglutide [15]

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All the figures were created with Biorender.com

This introduces the question of injection volume management