Am J Pathol 181(4):12151225 Nguyen DV, Linderholm A, Haczku A, Kenyon N (2017) Obesity-related, metabolic asthma: a new role for glucagon-like peptide 1 agonists
In addition, certain NDBs, such as lactoferrin-derived peptides, neutrophil peptides, and antimicrobial peptides (e.g., protegrin-1), have demonstrated antibacterial activity against intracellular pathogens, including Mycobacterium tuberculosis
By acting on both the GLP-1 and GIP receptors, tirzepatide reduces appetite, increases feelings of fullness, and helps patients consume fewer calories
Genetic and environmental influences on various phenotypes and disease risks have cross-generational heritability
Current animal model systems do not fully recapitulate the pathophysiological conditions in human IC/BPS, and targeting specific molecular pathway disruption in animal models might serve as a better option than existing models
Altered intestinal permeability, otherwise known as leaky gut, has also been found in 43% of individuals with autism, which leads to debilitating vitamin and mineral deficiencies
