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Side effects of Zofran Common side effects include: Headache Dizziness or lightheadedness Drowsiness Constipation or diarrhea Tiredness Serious side effects requiring immediate care: Allergic reaction: rash, hives, facial or throat swelling, breathing difficulty Serotonin syndrome: increased heart rate, sweating, muscle stiffness or spasms, fever, confusion Abnormal heart rhythm (QT prolongation): chest pain, heart rate changes, shortness of breath, severe dizziness Masking gastrointestinal blockage: lack of gas or bowel movements after surgery or chemotherapy Drug interactions Zofran may interact with other medications or supplements

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Next generation dual GLP-1/GIP, GLP-1/glucagon, and triple GLP-1/GIP/glucagon agonists: a literature review