Cell lines Stable CHO cell lines expressing human and mouse GLP-1R were generated in-house using standard methods as previously described 48
Nutrition in Clinical practice : Official Publication of the American Society for Parenteral and Enteral Nutrition, 32 (3), 365377
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Key warning signs of dehydration that patients should monitor include: Increased thirst and dry mouth that persists despite fluid intake Dark-colored urine or decreased urination frequency Dizziness or lightheadedness , especially when standing Fatigue and weakness beyond typical medication adjustment periods Headaches that are new or worsening Dry skin and decreased skin elasticity Rapid heartbeat or palpitations Certain patient populations face elevated dehydration risk, including older adults, individuals with pre-existing kidney disease, those taking diuretics, SGLT2 inhibitors, or other medications affecting fluid balance, and patients with diabetes who may have baseline fluid regulation challenges
In animal models, blocking IL-1 signaling (e.g., with anti-IL-1R antibodies) ameliorates Candida -exacerbated colitis (Li X.V
