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Experiments on different cancer cell types show that impairing the PI3K/AKT signaling pathway upregulates p21 and p27 43, 44, 45, 46 , two central inhibitors that can modify the cell cycle and halt proliferation

PMID: 41388589 Adv Mater Soft Extrudable Dendritic Particles with Nanostructured Tendrils for Local Adhesion and Drug Release to Bladder Cancers

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Nature (2016) 530(7588):516