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This stability underpins the entire rationale for oral dosing: a molecule that survives the stomach can plausibly exert effects directly on the gastrointestinal mucosa, and potentially be absorbed in functional form

Circulation 104 , 18941898 (2001)

Leeds, P

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Polygonatum sibiricum polysaccharide prevents depression-like behaviors by reducing oxidative stress, inflammation, and cellular and synaptic damage

it also suppresses the growth of platinum-resistant CRC and ovarian cancer cells, suggesting that combined treatments based on conventional drugs and glutamine-modulating compounds will yield clinically relevant results 43,44