exendin-4 vs glp-1 Competitive binding in INS-1 cells of [ 125 I]GLP-1 vs. various Strategies to Enhance the Therapeutic

Strengths Acts via multiple pathways (GLP-1, AMPK, microbiome) Has existing human data showing reductions in fasting glucose, HbA1c, lipids Support receptor expression and islet health Limitations Low absorption and bioavailability Gastrointestinal discomfort is common (diarrhea, cramping)

T.KivistK

Bachhawat AK, Thakur A, Kaur J, Zulkifli M

Diagnosis and Management of Hepatic Encephalopathy

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