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The NICE guideline has now introduced a maybe (indeterminate) range for the B12 test

(PubMed) Mares-Perlman JA, Brady WE, Klein BE, et al

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Discordant penetrance of the trait for familial amyloidotic polyneuropathy in two pairs of monozygotic twins

10.1007/s00726-011-1206-6 Summary Keywords Pichia pastoris, peptide-crossing-blood-brain-barrier, delta-sleepinducing peptide, neurotransmitter balance, mouse model, PCPA-induced insomnia Citation Mu X, Qu L, Yin L, Wang L, Liu X and Liu D (2024) Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models