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Due to their ability to interact with multiple partners, IDPs/IDRs can act scaffolds that orchestrate activities of partners (Cortese et al., 2008

Consequently, autophagy is important in providing nutrients to maintain cellular function under starvation, maintaining cellular homeostasis, and promoting cell survival under certain conditions

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Induction of Pdh and Pfkp by Exendin-4 was significantly blunted by HIF-1 knockdown (Fig