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and Smith, G.R

And that shift carries consequences

Increase fiber gradually, and pair it with fluids to avoid digestive discomfort

They minimize systemic inflammation by many mechanisms: direct suppression of pro-inflammatory cytokine synthesis (TNF-, IL-6, IL-1), augmentation of anti-inflammatory mediators (IL-10, adiponectin), and alteration of immune cell morphologies

Summary: Joint pain is not a common class-wide side effect of GLP-1 receptor agonists, though musculoskeletal symptoms are listed in some product summaries with varying frequency