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One common side effect of Zepbound and other GLP-1s for weight loss is that patients start to lose muscle

For people who are also dealing with blood sugar issues, this is when the 79% energy improvement statistic from the Mounjaro trials starts to make sense

Goldstein AL, Hannappel E, Kleinman HK (2005)

Semaglutide works by emulating the functions of a hormone called GLP-1, which tells your brain youre full and helps keep your blood sugar steady

After three weeks of treatment, body weights were 48 g in males and 50 g in females, whereas vehicle-treated mice showed a progressive increase in body weight, reaching 53 g (males) and 56 g (females) by the end of the study (Figure 1C)