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& Pati, S

FDA has also approved dapagliflozin for treatment for CKD (2021) [26] and has given priority review for empagliflozin to potentially treat heart failure not associated with left ventricular ejection fraction [27]

4 A Highly Competitive Market Ahead After patent expiry, multiple Indian pharmaceutical companies are expected to enter this space, making the GLP-1 segment one of the most competitive and high-growth therapy areas in the coming years

Sitagliptin (the first of the DPP-4 inhibitors) was launched on the market in 2006 [7]

Several lipid metabolites were found to be strongly associated with Adlercreutzia , including 2-methoxyestrone, ergosterol, 7-hydroxytestosterone, and PC 36:1, suggesting that this genus may exert regulatory effects by modulating steroid and PUFA metabolism