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Some patients prefer to add B12 as part of a broader weight-loss visit

They help keep cholesterol more soluble and lessen deposits in the blood vessels as well

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Stronger mechanistic clarification would require isoform-specific NOS inhibition, direct measurement of NO metabolites, eNOS phosphorylation analysis, rescue experiments, and comparison across endothelial, epithelial, fibroblast, and neuronal model systems

Treated wounds also show increased collagen deposition and enhanced angiogenesis, with new blood vessel formation supporting healing tissue with improved nutrient delivery