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Another study reported the interplay between ROS and SIRT1 in cell death during EV71 infection, and inhibition of ROS by NAC was shown to reduce EV71 propagation 149

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Integrating serial fluid measures with SPION/targeted MRI or PET may therefore yield a combined imaging and biomarker signature that improves early detection, helps distinguish progression from treatment effects, and supports treatment timing decisions (139, 140)

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10.1164/rccm.200509-1424OC

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