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MacMahon S, Peto R, Cutler J, Collins R, Sorlie P, Neaton J, et al

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Stronger documentationincluding documented weight trajectory, obesity-related comorbidities, or diabetes control metricsimproves approval likelihood

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If a lower exposure is clinically warranted, the approved product line generally already has a strength for it, and the route to that strength is a prescription not a modified device

MK 677 is also being researched for GH deficiency, especially in GH deficient adults, by stimulating endogenous GH secretion and improving body composition