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Melatonin regulation Melatonin, a hormone most commonly associated with sleep, is also linked to the aging process

These agents reduce the amount of proinflammatory cytokines, such as interleukin (IL) 17A and tumor necrosis factor- (TNF-) that play a role in keratinocyte hyperproliferation and the inflammation that characterizes psoriatic plaques

Avoid therapeutic doses unless medically indicated

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HF, heart failure

Managing lifestyle factors, such as reducing stress and quitting smoking, can also help improve symptoms