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The guideline text may include information or recommendations about certain drug uses ('off label') that are not approved by the Food and Drug Administration (FDA), or about medications or substances not subject to the FDA approval process

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Similarly, l-theanine, caffeine and their combination decreased reactivity of the DMN while exerting inhibitory control in the Stop-signal task possibly contributing to improved inhibitory control associated with l-theaninecaffeine combination

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6 There have however been other studies that failed to replicate these results

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