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amino acid supplementation should be tested as part of weight loss programmes to mitigate loss of skeletal muscle. In new observational research presented at ENDO2025, Melanie Haines and colleagues found that adequate protein intake was predictive of less muscle loss in patients receiving semaglutide for obesity

Novo Nordisk addressed this with a specialised absorption enhancer in oral semaglutide, though the requirement to take the medicine on an empty stomach with no more than 120ml of water, and to wait at least 30 minutes before eating or taking other medications, reflects the ongoing challenge of peptide absorption