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Han YM, Yoon H, Lim S, Sung MK, Shin CM, Park YS, et al

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The regulatory effect of GPX8 on Ca 2+ may be related to the inositol 1,4,5-triphosphate receptor (IP3R) effect, and the transmembrane domain (TMD) of GPX8 is thought to play a key role in the regulation of Ca 2+ signaling (Yoboue et al., 2017)

Researchers attribute these effects to Epithalons ability to restore normal p53 tumor suppressor gene expression, reduce oncogene activity, and re-normalize the cell cycle checkpoints that become dysregulated in aging tissues

A specific functional role for dopamine was suggested by the demonstration of its uncharacteristic distribution in the brain, separate from the distribution of noradrenaline