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These medications produce 15-21% average body weight reduction in clinical trials numbers that were unthinkable from pharmacotherapy even five years ago

Diabetes Obes Metab 24(1):94105 Zaazouee MS et al (2022) Semaglutide for the treatment of type 2 Diabetes Mellitus: A systematic review and network meta-analysis of safety and efficacy outcomes

Common negative themes include inconsistent medication quality, communication gaps, and difficulty obtaining refunds

Comparative efficacy and tolerability of currently approved incretin mimetics: a systematic analysis of placebo-controlled clinical trials

Gallbladder and biliary disease: GLP-1based therapies have been associated with an increased risk of gallbladder problems, including gallstones and cholecystitis

He suspected this was due to the hormone stimulating the release of insulin independently of its ability to raise blood glucose levels