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To view a copy of this licence, visit About this article Cite this article Nakai, T., Hirata, K., Nagano, K

10.1007/s12020-019-02055-z 8 CasesA

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In a surgically induced-OA model in rats, liraglutide also attenuated rat cartilage degeneration through suppressing the release of inflammatory mediators and protected chondrocytes against endoplasmic reticulum (ER) stress and apoptosis induced by interleukin-1 (IL-1) or triglycerides [46]

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The TRIUMPH cardiovascular outcomes trial will determine whether these surrogate marker improvements translate to fewer actual cardiovascular events