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Despite significant improvements in patient prognosis over recent decades through therapeutic advancesincluding proteasome inhibitors (PIs), immunomodulatory drugs (IMiDs), monoclonal antibodies, bispecific antibodies, and chimeric antigen receptor T-cell immunotherapy (CAR-T) (Rajkumar and Kumar, 2020), the disease remains incurable due to inevitable relapse and drug resistance during maintenance therapy

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E., Oeltzschner, G., & Edden, R

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