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This single-pathway mechanism has been extensively studied in millions of patients and consistently produces weight loss of 1522% of body weight over 68 weeks in clinical trials

Both doses of tirzepatide also resulted in a greater proportion of patients achieving the secondary endpoint of 25% weight reduction compared to the placebo for both estimands ( Figure 9 - 20C-D )

For example, FDA-approved semaglutide products typically begin at 0 } Why Patients Consider Lower Doses Interest in microdosing GLP-1 usually centers around three practical concerns