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6 Reduction of AMPK expression mitigates the impact of exendin-4 on BACE1-mediated APP processing

However, components of obesity pathology -particularly IR and low-grade inflammation- may impair these protective mechanisms, thereby contributing to the development of SO

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Adjustments to the dosing schedule, additional supportive medications, or consideration of alternative weight management strategies may be appropriate

In these cases, there can be a significant amount wasted

This remains its primary use, but it became increasingly common for doctors to prescribe it to obese patients off-label as a treatment to control weight