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10.1016/j.bpobgyn.2010.10.016 Best Pract

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The overexpression of ROS leads to the polarization of macrophages toward pro-inflammatory M1 phenotype, which secrete interleukin-6 (IL-6), interleukin-1 (IL-1), tumor necrosis factor- (TNF-) and other inflammation cytokines possessing negative effects on the physiological activities of BMSCs 38

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