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Ablation of autophagy-related E1 Ligase Atg7 Primes Acute Myelogenous Leukemia Cells to Apoptosis, Sensitizes to Chemotherapy and Overcomes Stroma Mediated Protection

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Consistent with what we reported while studying endothelial cells [30], we found that ALCAR downregulates in PCa cells the release of pro-angiogenic factors involved in inflammation and endothelial recruitment and activation such as VEGF, CXCL8, CCL2 and CXCL12