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403.93 g/mol (Cu complex) Mechanism: copper-dependent regulation of collagen, elastin, and antioxidant gene expression in dermal and connective tissue Regulatory status: not approved by the FDA or EMA

Interestingly, low blood levels of vitamin B12 have been linked with reduced bone mass, though clinical trials have not definitively supported the efficacy of B vitamin supplements in treating fractures ( Recent research states that the role of vitamin B12 and bone health is not well established

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