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Chronic sleep insufficiency and rhythm disruption in the elderly can exacerbate metabolic syndrome (hypertension, insulin resistance, dyslipidemia) and promote neuropsychiatric problems (Touitou et al., 2017)

doi: 10.2147/CIA.S443572

Brewers yeast is a byproduct of beer-making and used in making bread

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This latter induced the formation of reactive oxygen species (ROS) in the hepatocytes resulting in the increase in cellular thiobarbituric acid reactive substances (TBARS) and glutathione (GSH) depletion

Materials and methods Strains, Plasmids and growth conditions Bacterial strains and plasmids used in this study are listed in Supplementary tables S1 and S2