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Kiousi DE, Kouroutzidou AZ, Neanidis K, Matthaios D, Pappa A, Galanis A (2022) Evaluating the role of probiotics in the prevention and management of age-related diseases

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A separate recent study in the Journal of the American Academy of Dermatology with more than 1 million participants worldwide found significantly higher risks of various subtypes of alopecia with GLP-1 drugs than with the commonly used diabetes drug metformin

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Therefore, these aforementioned compounds represent promising skin-whitening agents, but those targeting TYR gene expression are not recommended for clinical use mainly for their non-specific effects through intracellular signaling cascades (73)