White et al., 2021), which may limit fetal growth potential
After 60, several critical systems are in decline simultaneously: Growth hormone (GH) secretion drops significantly with age, reducing IGF-1 levels that govern muscle maintenance, fat metabolism, and tissue repair Insulin sensitivity worsens progressively, increasing metabolic syndrome risk Inflammatory signalling chronic low-grade inflammation ("inflammaging") accelerates cellular damage Sleep architecture slow-wave sleep decreases, impairing the overnight GH pulse that drives recovery Peptides that target the GH axis secretagogues like sermorelin, CJC-1295, and ipamorelin work by stimulating the pituitary to release more of your own growth hormone
doi: 10.1164/ajrccm.154.6.8970383 171 MeldrumOWChotirmallSH
Journal of Clinical Endocrinology & Metabolism , 93(8), 3026-3032
CordenPharma is a major CDMO with significant US operations, particularly in Colorado, that specializes in taking peptide projects from early development through commercial manufacturing
How PlexusDx Supports a More Personalized Approach PlexusDx's Precision Peptide Genetic Test may help provide context around your individual metabolic predispositions by examining variants in GLP-1 and metabolic pathways (such as GIPR rs1800437 and FTO rs9939609)
