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Endogenous antioxidants, including glutathione, glutathione peroxidase, catalase, and superoxide dismutase, and exogenous antioxidants, including vitamins C, E, carotenoids, selenium, and zinc, help counteract oxidative stress and protect adrenals (Patani 2023)
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Additionally, CYP24A1 showed it upregulated mRNA and protein expression in hepatocytes treated with GCLC siRNA or its inhibitor