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Additionally, severe ischemic neuronal degeneration associated with atrophy, loss of cytoplasmic and nuclear architectures, consequent atrophy of the granular layer, and rarefaction of the molecular layer were observed

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Extending the data exclusivity or patent protection period on a biologic through legitimate lifecycle management adding an FDA-approved new indication, for example extends the period during which the manufacturer can negotiate rebates from a position of formulary necessity rather than formulary competition

Zepbound is a GIP and GLP-1 receptor agonist

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