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Furthermore, typical side effects associated with the use of such drugs, including nausea and digestion problems, have resulted in an increased interest of consumers in products that do not cause discomfort and which are easily digestible, low on sugar and with controlled portions

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The combination treatment showed greater neuroprotection compared to curcumin alone, suggesting piperine as a bioavailability enhancer of curcumin (Singh et al., 2015)