Find articles by Baggio, L
Furthermore, GLP-1-based medications such as GLP-1 receptor agonists and dipeptidyl peptidase-4 inhibitors, have been shown to improve diabetes control in preclinical and clinical trials with human subjects
Due to its insulinotropic action (stimulates insulin secretion), GLP-1-based treatments effectively prevent postprandial hyperglycemia (post-meal glucose spikes) in patients with T2DM
A subset of participants with obstructive sleep apnea is also included
Both GLP-1 (7-36) and GLP-1 (7-37) also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin
13-16 weeks : After assessment, your doctor will escalate the dosage to 8 mg once weekly for the next 4 weeks 17-21 weeks : If your body tolerates 8 mg for 4 weeks, your doctor will increase the dose to 12 mg once weekly onwards