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Studies have also shown the potential of the DPP-4 inhibitor alogliptin in increasing production of brain-derived neurotrophic factor (BDNF), leading to decrease toxic release of glutamate [67]

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Binding of the ligand (GLP-1) or its analog on the extracellular side of the protein induces conformational changes that are sensed by the G-proteins on the cytoplasmic face - initiating a signaling cascade (see Figure 3 a and b)

doi: 10.1007/s00125-008-1053-5 160 ChristensenMMHHjlundKHother-NielsenOStageTBDamkierPBeck-NielsenHet al

Food or liquid accidentally enters the lungs while a person is under anesthesia or very deeply sedated