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(A) Overview of experimental procedure

For the HEDS assays, either GSH was varied between 100 M and 1.5 mM for ScGrx (or 250 M and 3.0 mM for PfGrx) at fixed concentrations of HEDS (0.18, 0.37, 0.55 and 0.74 mM) or HEDS was varied between 90 and 920 M at fixed concentrations of GSH (0.3, 0.5, 1 and 1.5 mM for ScGrx7 or 0.25, 0.5, 1 and 2 mM for PfGrx)

Importantly, the favorable effect could be attributed to the capacity of some oligomeric forms to influence the proliferation of androgen-resistant and androgen-sensitive human prostate cancer cell lines [92]

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B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis