A similar pathway was shown to be involved in the release of insulin in response to TGR5 ligands in pancreatic cells (Kumar et al., Figure 5 Inhibition of OA-induced GLP-1 and PYY release by H 2 S To investigate the regulation of TGR5-mediated GLP-1 and PYY release by H 2 S, cells were incubated with L-cysteine, an activator of endogenous enzymes CSE and CBS, for 10 min and then GLP-1 and PYY release in response to OA was measured
La sibutramina, un principio activo anorexgeno que suprime el apetito y aumenta el gasto calrico, puede tener efectos adversos significativos, como aumento de la frecuencia cardiaca y la presin sangunea
Weiner, Evaluation of treatment effects in Alzheimers and other neurodegenerative diseases by MRI and MRS
Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, Mclauchlan H, et al (2007) The selectivity of protein kinase inhibitors: a further update
As well as affecting pigment cells in the skin, the drug can bind to receptors in the brain and influence processes like appetite and sexual function
Liatsopoulou A, Varvaresou A, Mellou F, Protopapa E
