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The shift toward injectable therapies with proven cardiovascular benefits (e.g., Ozempic) affects demand for older drugs like Byetta

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In others particularly at higher doses or during dose escalation the net effect may be altered intestinal motility and transit patterns that result in looser stools or diarrhoea

Lancet, 344 , 796798

Adherence to these principles facilitates safe and effective application in the research setting and conservation of integrity within an experiment

It helps convert harmful compounds into less toxic forms that can be eliminated from the body